Shen-Ying ZHANG | Institut Imagine

Presentation

Shen-Ying ZHANG

Human genetics of infectious diseases

Contact :

shen-ying.zhang@inserm.fr

About

Scientific Publications

Publications

2026

Humans homozygous for rare or common hypomorphic IL23R variants are prone to ..., J Exp Med
2026

Autoantibodies neutralizing type I IFNs in 40% of patients with WNV encephali..., J Hum Immun
2026

Human LFA-1 governs T cell immune surveillance of the skin., Sci Immunol
2024

Autoinflammation in patients with leukocytic CBL loss of heterozygosity is ca..., J Clin Invest
2024

Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I I..., J Exp Med
2024

Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalit..., J Exp Med
2024

A sensitive assay for measuring whole-blood responses to type I IFNs., Proc Natl Acad Sci U S A
2024

Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 i..., HGG Adv
2024

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-..., J Exp Med
2023

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs n..., Sci Immunol
2023

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis..., J Exp Med
2023

Rare predicted loss-of-function variants of type I IFN immunity genes are ass..., Genome Med
2023

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria., Cell
2022

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneu..., J Exp Med
2022

The risk of COVID-19 death is much greater and age dependent with type I IFN ..., Proc Natl Acad Sci U S A
2021

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life..., Sci Immunol
2021

Autoantibodies neutralizing type I IFNs are present in 4% of uninfected indiv..., Sci Immunol
2021

A monocyte/dendritic cell molecular signature of SARS-CoV-2-related multisyst..., Med
2021

Polyclonal expansion of TCR Vbeta 21.3 CD4 and CD8 T cells is a hallmark of M..., Sci Immunol
2021

A computational approach for detecting physiological homogeneity in the midst..., Am J Hum Genet
2021

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever..., J Exp Med
2020

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19., Science
2020

Autoantibodies against type I IFNs in patients with life-threatening COVID-19., Science
2019

Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 a..., Nat Med
2019

Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reacti..., J Exp Med
2019

Severe influenza pneumonitis in children with inherited TLR3 deficiency., J Exp Med
2019

Human inborn errors of immunity to infection affecting cells other than leuko..., Curr Opin Immunol
2018

PopViz: a webserver for visualizing minor allele frequencies and damage predi..., Bioinformatics
2018

Life-threatening influenza pneumonitis in a child with inherited IRF9 deficie..., J Exp Med
2018

Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection., Cell
2017

Autosomal Recessive Cardiomyopathy Presenting as Acute Myocarditis., J Am Coll Cardiol
2010

Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 a..., Immunity
2007

TLR3 deficiency in patients with herpes simplex encephalitis., Science

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Presentation

About

Scientific Publications

Humans homozygous for rare or common hypomorphic IL23R variants are prone to ..., J Exp Med

Autoantibodies neutralizing type I IFNs in 40% of patients with WNV encephali..., J Hum Immun

Human LFA-1 governs T cell immune surveillance of the skin., Sci Immunol

Autoinflammation in patients with leukocytic CBL loss of heterozygosity is ca..., J Clin Invest

Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I I..., J Exp Med

Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalit..., J Exp Med

A sensitive assay for measuring whole-blood responses to type I IFNs., Proc Natl Acad Sci U S A

Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 i..., HGG Adv

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-..., J Exp Med

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs n..., Sci Immunol

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis..., J Exp Med

Rare predicted loss-of-function variants of type I IFN immunity genes are ass..., Genome Med

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria., Cell

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneu..., J Exp Med

The risk of COVID-19 death is much greater and age dependent with type I IFN ..., Proc Natl Acad Sci U S A

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life..., Sci Immunol

Autoantibodies neutralizing type I IFNs are present in 4% of uninfected indiv..., Sci Immunol

A monocyte/dendritic cell molecular signature of SARS-CoV-2-related multisyst..., Med

Polyclonal expansion of TCR Vbeta 21.3 CD4 and CD8 T cells is a hallmark of M..., Sci Immunol

A computational approach for detecting physiological homogeneity in the midst..., Am J Hum Genet

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever..., J Exp Med

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19., Science

Autoantibodies against type I IFNs in patients with life-threatening COVID-19., Science

Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 a..., Nat Med

Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reacti..., J Exp Med

Severe influenza pneumonitis in children with inherited TLR3 deficiency., J Exp Med

Human inborn errors of immunity to infection affecting cells other than leuko..., Curr Opin Immunol

PopViz: a webserver for visualizing minor allele frequencies and damage predi..., Bioinformatics

Life-threatening influenza pneumonitis in a child with inherited IRF9 deficie..., J Exp Med

Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection., Cell

Autosomal Recessive Cardiomyopathy Presenting as Acute Myocarditis., J Am Coll Cardiol

Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 a..., Immunity

TLR3 deficiency in patients with herpes simplex encephalitis., Science